Logo

American Heart Association

  9
  0


Final ID: Sa1120

Extracorporeal Shockwave Therapy Improves Physical Outcomes and Quality of Life In Patients With Symptomatic Peripheral Arterial Disease: Results from a Meta-analysis of Randomized Controlled Trials

Abstract Body (Do not enter title and authors here):
Introduction
Extracorporeal shockwave therapy (ESWT) is a non-invasive procedure that may be useful to treat symptomatic peripheral arterial disease (PAD). Trials comparing ESWT with control groups have shown promising results.
Methods
PubMed, Cochrane, EMBASE, and Google Scholar were searched for randomized controlled trials reporting the efficacy of extracorporeal shockwave therapy versus control in patients with symptomatic PAD. Data from eligible studies was analyzed using the Review Manager 5.4 software. Mean difference (MD) and 95% Confidence intervals (CI) were calculated for continuous outcomes. Inverse variance method and a random effects model were used for pooled estimates. A p-value < 0.05 (Z-test) was considered significant.
Results
5 randomized controlled trials with 264 patients were included in our analysis. A significant increase in the mean walking distance (MD: 54.13, 95% CI 9.34 to 98.92, p=0.02), pain-free walking distance (MD: 54.13, 95% CI 14.19, 57.88, p= 0.001), SF-36 physical component summary (MD: 11.97, 95% CI 0.26 to 23.69, p=0.05), EQ-5D-3L index score (MD; 0.08, 95% CI: 0.00 to 0.15, p=0.05) and VascuQoL index ((MD: 0.48, 95% CI 0.03 to 0.92, p= 0.04) was seen with ESWT. A slightly higher ankle brachial pressure index was seen in the control group (MD: -0.01, 95% CI: -0.02 to -0.00, p=0.04). There was no difference in SF-36 physical functioning domain score (MD: 18.58, 95% CI: -0.29 to 37.45, p=0.05) and SF-36 bodily pain score (MD: 9.17, 95% CI: -2.885 to 21.19, p=0.13).
Conclusions
There was significant improvement in walking distances, exertional symptoms, and quality of life with ESWT. However, ESWT did not translate to an increase in post-treatment ankle-brachial index which was slightly higher in the control group. There is a need for larger randomized controlled trials to substantiate the efficacy of ESWT in treating symptomatic PAD.
  • Kashif, Talha  ( King Edward Medical University , Lahore , Pakistan )
  • Rahman, Ummi Aiman  ( King Edward Medical University , Lahore , Pakistan )
  • Qureshi, Ali Akram  ( King Edward Medical University , Lahore , Pakistan )
  • Mubashir, Mohammad Maheer  ( King Edward Medical University , Lahore , Pakistan )
  • Alvi, Fatima  ( Fatima Jinnah Medical University , Lahore , Pakistan )
  • Qureshi, Muhammad Ahmad  ( Henry Ford Jackson Hospital , Jackson , Michigan , United States )
  • Author Disclosures:
    Talha Kashif: No Answer | Ummi Aiman Rahman: DO NOT have relevant financial relationships | Ali Akram Qureshi: DO NOT have relevant financial relationships | Mohammad Maheer Mubashir: DO NOT have relevant financial relationships | Fatima Alvi: No Answer | Muhammad Ahmad Qureshi: DO NOT have relevant financial relationships
Meeting Info:

Scientific Sessions 2024

2024

Chicago, Illinois

Session Info:

From Lungs to Toes, WAZE Around Peripheral Clots and Blocks

Saturday, 11/16/2024 , 02:00PM - 03:00PM

Abstract Poster Session

More abstracts on this topic:
Changes in EQ-5D-5L with Aficamten in Obstructive Hypertrophic Cardiomyopathy (oHCM): the SEQUOIA-HCM Trial

Schulze Christian, Kwong Raymond, Maron Martin, Masri Ahmad, Nassif Michael, Olivotto Iacopo, Spertus John, Veselka Josef, Butzner Michael, Heitner Stephen, Jacoby Daniel, Abraham Theodore, Kupfer Stuart, Malik Fady, Meng Lixin, Shreay Sanatan, Wohltman Amy, Maurer Mathew, Barriales-villa Roberto, Claggett Brian, Coats Caroline, Garcia-pavia Pablo, Hagege Albert, Januzzi James, Kulac Ian

Association Between Lp(a) and Cardiovascular Events in Individuals with Peripheral Artery Disease in the Mass General Brigham Lp(a) Registry

Mcclintick Daniel, Gerhard Marie, Januzzi James, Di Carli Marcelo, Secemsky Eric, Bhatt Deepak, Blankstein Ron, Divakaran Sanjay, Biery David, Berman Adam, Besser Stephanie, Shiyovich Arthur, Singh Avinainder, Huck Daniel, Weber Brittany, Bonaca Marc

More abstracts from these authors:
Evaluating risk factors of embolism in patients with cardiac myxoma: A systematic review and meta-analysis

Qureshi Muhammad Ahmad, Hussain Muqaddas, Qureshi Ali Akram, Bakht Danyal, Ahmed Omair, Haseeb Shahan, Gupta Kartik, Baqal Omar, Hadeed Khawar Mirza Muhammad, Amir Maaz, Ali Khawar

Comparison of 30-Day Outcomes of TAVR vs. SAVR in Patients with Prior CABG: A Meta-Analysis

Qureshi Muhammad Ahmad, Munir Shafia, Zulqarnain Muhammad, Qureshi Ali Akram, Haseeb Shahan, Bakht Danyal, Amir Maaz, Hussain Muqaddas, Ahmed Omair, Rehman Aqeeb Ur, Ahmed Hafsa, Ansari Umair

You have to be authorized to contact abstract author. Please, Login
Not Available